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Carbenoxolone disodium

CAS No. 7421-40-1

Carbenoxolone disodium( Biogastrone | Bioral | Carbenoxolone sodium | Duogastrone | Pyrogastrone | Sanodin )

Catalog No. M15836 CAS No. 7421-40-1

An agent derived from licorice root. It is used for the treatment of digestive tract ulcers, especially in the stomach. Antidiuretic side effects are frequent, but otherwise the drug is low in toxicity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Carbenoxolone disodium
  • Note
    Research use only, not for human use.
  • Brief Description
    An agent derived from licorice root. It is used for the treatment of digestive tract ulcers, especially in the stomach. Antidiuretic side effects are frequent, but otherwise the drug is low in toxicity.
  • Description
    An agent derived from licorice root. It is used for the treatment of digestive tract ulcers, especially in the stomach. Antidiuretic side effects are frequent, but otherwise the drug is low in toxicity.
  • In Vitro
    Cell Viability Assay Cell Line:HaCaT cells Concentration:6 μM, 12 μM, 30 μM, 60 μM, 150 μM Incubation Time:Pre-treatment 1 hour Result:Had no toxicity until 48 hours at high dose in virus-infected cells. Western Blot Analysis Cell Line:HaCaT cells Concentration:30 μM Incubation Time:Pre-treatment 1 hour Result:Presented an obvious upregulation of A27.
  • In Vivo
    ——
  • Synonyms
    Biogastrone | Bioral | Carbenoxolone sodium | Duogastrone | Pyrogastrone | Sanodin
  • Pathway
    Cytoskeleton/Cell Adhesion Molecules
  • Target
    Gap Junction Protein
  • Recptor
    Gap Junction Protein
  • Research Area
    Inflammation/Immunology
  • Indication
    Psoriasis

Chemical Information

  • CAS Number
    7421-40-1
  • Formula Weight
    614.72
  • Molecular Formula
    C34H48Na2O7
  • Purity
    >98% (HPLC)
  • Solubility
    Water: 100 mM
  • SMILES
    CC(C)([C@](CC[C@@]([C@@]1(CC[C@]2(CC[C@](C([O-])=O)(C[C@]2(C1=C3)[H])C)C)C)4C)5[H])[C@@H](OC(CCC([O-])=O)=O)CC[C@]5(C)[C@@]4([H])C3=O.[Na+].[Na+]
  • Chemical Name
    sodium (2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bR)-10-((3-carboxylatopropanoyl)oxy)-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-2-carboxylate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Hausmann W, Tárnoky AL. Br J Pharmacol ChemOthers. 1966 Feb;26(2):412-20.
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